Donors with group B KIR haplotypes improve relapse-free survival after unrelated hematopoietic cell transplantation for acute myelogenous leukemia

Survival for patients with acute myeloid leukemia (AML) is limited by treatment-related mortality (TRM) and relapse after unrelated donor (URD) hematopoietic cell transplantation (HCT). Natural killer (NK)–cell alloreactivity, determined by donor killer-cell immunoglobulin-like receptors (KIRs) and...

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Autori principali: Cooley, Sarah, Trachtenberg, Elizabeth, Bergemann, Tracy L., Saeteurn, Koy, Klein, John, Le, Chap T., Marsh, Steven G. E., Guethlein, Lisbeth A., Parham, Peter, Miller, Jeffrey S., Weisdorf, Daniel J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2009
Soggetti:
Transplantation
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2628378/
https://ncbi.nlm.nih.gov/pubmed/18945962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-07-171926
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