Donor selection for natural killer cell receptor genes leads to superior survival after unrelated transplantation for acute myelogenous leukemia

Killer-cell immunoglobulin-like receptor (KIR) genes form a diverse, immunogenetic system. Group A and B KIR haplotypes have distinctive centromeric (Cen) and telomeric (Tel) gene-content motifs. Aiming to develop a donor selection strategy to improve transplant outcome, we compared the contribution...

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Autors principals: Cooley, Sarah, Weisdorf, Daniel J., Guethlein, Lisbeth A., Klein, John P., Wang, Tao, Le, Chap T., Marsh, Steven G. E., Geraghty, Daniel, Spellman, Stephen, Haagenson, Michael D., Ladner, Martha, Trachtenberg, Elizabeth, Parham, Peter, Miller, Jeffrey S.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2010
Matèries:
Plenary Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2953880/
https://ncbi.nlm.nih.gov/pubmed/20581313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-05-283051
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