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Chokepoints in Mechanical Coupling Associated with Allosteric Proteins: The Pyruvate Kinase Example

Although the critical role of allostery in controlling enzymatic processes is well appreciated, there is a current dearth in our understanding of its underlying mechanisms, including communication between binding sites. One potential key aspect of intersite communication is the mechanical coupling b...

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Bibliographische Detailangaben
Veröffentlicht in:Biophys J
Hauptverfasser: Johnson, Lewis E., Ginovska, Bojana, Fenton, Aron W., Raugei, Simone
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Biophysical Society 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6510705/
https://ncbi.nlm.nih.gov/pubmed/31010662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.03.026
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