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Identification of allosteric-activating drug leads for human liver pyruvate kinase
There is a growing appreciation of the beneficial attributes of allosteric drugs. However, the development of this special class of drugs has in large part been via serendipitous findings from high-throughput screens of drug libraries. Limited success at deliberately identifying allosteric drugs may...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3695698/ https://ncbi.nlm.nih.gov/pubmed/22052501 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-61779-334-9_20 |
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