Improvement of in vitro and early in utero porcine clone development after somatic donor cells are cultured under hypoxia

Genetically engineered pigs serve as excellent biomedical and agricultural models. To date, the most reliable way to generate genetically engineered pigs is via somatic cell nuclear transfer (SCNT), however, the efficiency of cloning in pigs is low (1–3%). Somatic cells such as fibroblasts frequentl...

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Dades bibliogràfiques
Publicat a:Mol Reprod Dev
Autors principals: Mordhorst, Bethany R., Benne, Joshua A., Cecil, Raissa F., Whitworth, Kristin M., Samuel, Melissa S., Spate, Lee D., Murphy, Clifton N., Wells, Kevin D., Green, Jonathan A., Prather, Randall S.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2019
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6510642/
https://ncbi.nlm.nih.gov/pubmed/30779254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mrd.23132
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