Improvement of in vitro and early in utero porcine clone development after somatic donor cells are cultured under hypoxia

Genetically engineered pigs serve as excellent biomedical and agricultural models. To date, the most reliable way to generate genetically engineered pigs is via somatic cell nuclear transfer (SCNT), however, the efficiency of cloning in pigs is low (1–3%). Somatic cells such as fibroblasts frequentl...

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Detalhes bibliográficos
Publicado no:Mol Reprod Dev
Main Authors: Mordhorst, Bethany R., Benne, Joshua A., Cecil, Raissa F., Whitworth, Kristin M., Samuel, Melissa S., Spate, Lee D., Murphy, Clifton N., Wells, Kevin D., Green, Jonathan A., Prather, Randall S.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
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Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6510642/
https://ncbi.nlm.nih.gov/pubmed/30779254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mrd.23132
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