Oxamflatin Treatment Enhances Cloned Porcine Embryo Development and Nuclear Reprogramming(*)

Faulty epigenetic reprogramming of somatic nuclei is thought to be the main reason for low cloning efficiency by somatic cell nuclear transfer (SCNT). Histone deacetylase inhibitors (HDACi), such as Scriptaid, improve developmental competence of SCNT embryos in several species. Another HDACi, Oxamfl...

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Veröffentlicht in:Cell Reprogram
Hauptverfasser: Mao, Jiude, Zhao, Ming-Tao, Whitworth, Kristin M., Spate, Lee D., Walters, Eric M., O'Gorman, Chad, Lee, Kiho, Samuel, Melissa S., Murphy, Clifton N., Wells, Kevin, Rivera, Rocio M., Prather, Randall S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Mary Ann Liebert, Inc. 2015
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4312790/
https://ncbi.nlm.nih.gov/pubmed/25548976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cell.2014.0075
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