Oxamflatin Treatment Enhances Cloned Porcine Embryo Development and Nuclear Reprogramming(*)

Faulty epigenetic reprogramming of somatic nuclei is thought to be the main reason for low cloning efficiency by somatic cell nuclear transfer (SCNT). Histone deacetylase inhibitors (HDACi), such as Scriptaid, improve developmental competence of SCNT embryos in several species. Another HDACi, Oxamfl...

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Dettagli Bibliografici
Pubblicato in:Cell Reprogram
Autori principali: Mao, Jiude, Zhao, Ming-Tao, Whitworth, Kristin M., Spate, Lee D., Walters, Eric M., O'Gorman, Chad, Lee, Kiho, Samuel, Melissa S., Murphy, Clifton N., Wells, Kevin, Rivera, Rocio M., Prather, Randall S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mary Ann Liebert, Inc. 2015
Soggetti:
Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4312790/
https://ncbi.nlm.nih.gov/pubmed/25548976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cell.2014.0075
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