Effects of Combined Treatment of MG132 and Scriptaid on Early and Term Development of Porcine Somatic Cell Nuclear Transfer Embryos

Although improving, the efficiency of producing offspring by somatic cell nuclear transfer (SCNT) is still low (<1.5%). Our laboratory has demonstrated that histone deacetylase inhibitor (Scriptaid) treatment of reconstructed embryos enhances blastocyst formation and cloning efficiency in pigs. I...

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Autori principali: Mao, Jiude, Tessanne, Kimberly, Whitworth, Kristin M., Spate, Lee D., Walters, Eric M., Samuel, Melissa S., Murphy, Clifton N., Tracy, Lisa, Zhao, Jianguo, Prather, Randall S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mary Ann Liebert, Inc. 2012
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Brief Communication
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3459054/
https://ncbi.nlm.nih.gov/pubmed/22917492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cell.2012.0018
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