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Genome mining and biosynthesis of kitacinnamycins as a STING activator

Cinnamoyl-containing nonribosomal peptides (CCNPs) are a small group of secondary metabolites with potent biological activities produced by actinobacteria. Two remarkable features in the biosynthesis of CCNPs include the nonribosomal peptide synthases (NRPSs) for assembly of the depsipeptide backbon...

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Detalles Bibliográficos
Publicado en:Chem Sci
Main Authors: Shi, Jing, Liu, Cheng Li, Zhang, Bo, Guo, Wen Jie, Zhu, Jiapeng, Chang, Chin-Yuan, Zhao, Er Juan, Jiao, Rui Hua, Tan, Ren Xiang, Ge, Hui Ming
Formato: Artigo
Idioma:Inglês
Publicado: Royal Society of Chemistry 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6510318/
https://ncbi.nlm.nih.gov/pubmed/31160959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9sc00815b
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