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Enzyme-catalysed [6+4] cycloadditions in the biosynthesis of natural products
Pericyclic reactions are powerful transformations for the construction of carbon–carbon and carbon–heteroatom bonds in organic synthesis. Their role in biosynthesis is increasingly apparent, and mechanisms by which pericyclases can catalyse reactions are of major interest(1). [4+2] cycloadditions (D...
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| Publicat a: | Nature |
|---|---|
| Autors principals: | , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6944468/ https://ncbi.nlm.nih.gov/pubmed/30867595 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-019-1021-x |
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