Discovery and biosynthesis of guanipiperazine from a NRPS-like pathway

Nonribosomal peptide synthetases (NRPSs) are modular enzymes that use a thiotemplate mechanism to assemble the peptide backbones of structurally diverse and biologically active natural products in bacteria and fungi. Unlike these canonical multi-modular NRPSs, single-module NRPS-like enzymes, which...

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Publicado en:Chem Sci
Autores principales: Shi, Jing, Xu, Xiang, Liu, Pei Yi, Hu, Yi Ling, Zhang, Bo, Jiao, Rui Hua, Bashiri, Ghader, Tan, Ren Xiang, Ge, Hui Ming
Formato: Artigo
Lenguaje:Inglês
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8179380/
https://ncbi.nlm.nih.gov/pubmed/34164059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0sc06135b
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