Comparative genome mining and heterologous expression of an orphan NRPS gene cluster direct the production of ashimides

The ever-increasing bacterial genomic repositories reveal a great number of uncharacterized biosynthetic gene clusters, representing a tremendous resource for natural product discovery. Genome mining of the marine Streptomyces sp. NA03103 indicates the presence of an orphan nonribosomal peptide synt...

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Bibliographic Details
Published in:Chem Sci
Main Authors: Shi, Jing, Zeng, Ying Jie, Zhang, Bo, Shao, Fen Li, Chen, Yan Chi, Xu, Xiang, Sun, Yang, Xu, Qiang, Tan, Ren Xiang, Ge, Hui Ming
Format: Artigo
Language:Inglês
Published: Royal Society of Chemistry 2019
Subjects:
Chemistry
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6427947/
https://ncbi.nlm.nih.gov/pubmed/30996885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8sc05670f
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