EZH2 Regulates Protein Stability via Recruiting USP7 to Mediate Neuronal Gene Expression in Cancer Cells

Misexpression of chromatin modification factors and changed epigenetic modifications play crucial roles for tumorigenesis. Our previous studies demonstrated that inhibition of epigenetic modification enzymes EZH2, LSD1, DNMTs, and HDACs caused post-mitotic neuron-like differentiation in different ca...

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Bibliographic Details
Published in:Front Genet
Main Authors: Lei, Anhua, Chen, Lu, Zhang, Min, Yang, Xiaoli, Xu, Liyang, Cao, Ning, Zhang, Zan, Cao, Ying
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2019
Subjects:
Genetics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6510286/
https://ncbi.nlm.nih.gov/pubmed/31130994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2019.00422
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