JmjC Domain-containing Protein 6 (Jmjd6) Derepresses the Transcriptional Repressor Transcription Factor 7-like 1 (Tcf7l1) and Is Required for Body Axis Patterning during Xenopus Embryogenesis

Tcf7l1 (also known as Tcf3) is a bimodal transcription factor that plays essential roles in embryogenesis and embryonic and adult stem cells. On one hand, Tcf7l1 works as transcriptional repressor via the recruitment of Groucho-related transcriptional corepressors to repress the transcription of Wnt...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Zhang, Xuena, Gao, Yan, Lu, Lei, Zhang, Zan, Gan, Shengchun, Xu, Liyang, Lei, Anhua, Cao, Ying
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2015
Fag:
Developmental Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4536435/
https://ncbi.nlm.nih.gov/pubmed/26157142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.646554
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