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USP7 stabilizes EZH2 and enhances cancer malignant progression

EZH2, a histone methylase, plays a critical role in the tumor progression via regulation of progenitor genes. However, the detailed molecular mechanism of EZH2 in cancer malignant progression remains unknown. Therefore, we aimed to investigate how EZH2 is regulated in human cancer. We used numerous...

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Publicat a:Am J Cancer Res
Autors principals: Zheng, Nana, Chu, Man, Lin, Min, He, Youhua, Wang, Zhiwei
Format: Artigo
Idioma:Inglês
Publicat: e-Century Publishing Corporation 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7017725/
https://ncbi.nlm.nih.gov/pubmed/32064169
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