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Oncogenic Roles and Inhibitors of DNMT1, DNMT3A, and DNMT3B in Acute Myeloid Leukaemia

Epigenetic alteration has been proposed to give rise to numerous classic hallmarks of cancer. Impaired DNA methylation plays a central role in the onset and progression of several types of malignancies, and DNA methylation is mediated by DNA methyltransferases (DNMTs) consisting of DNMT1, DNMT3A, an...

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Foilsithe in:Biomark Insights
Main Authors: Wong, Kah Keng, Lawrie, Charles H, Green, Tina M
Formáid: Artigo
Teanga:Inglês
Foilsithe: SAGE Publications 2019
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6509988/
https://ncbi.nlm.nih.gov/pubmed/31105426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1177271919846454
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