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Oncogenic Roles and Inhibitors of DNMT1, DNMT3A, and DNMT3B in Acute Myeloid Leukaemia

Epigenetic alteration has been proposed to give rise to numerous classic hallmarks of cancer. Impaired DNA methylation plays a central role in the onset and progression of several types of malignancies, and DNA methylation is mediated by DNA methyltransferases (DNMTs) consisting of DNMT1, DNMT3A, an...

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Podrobná bibliografie
Vydáno v:Biomark Insights
Hlavní autoři: Wong, Kah Keng, Lawrie, Charles H, Green, Tina M
Médium: Artigo
Jazyk:Inglês
Vydáno: SAGE Publications 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6509988/
https://ncbi.nlm.nih.gov/pubmed/31105426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1177271919846454
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