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Oncogenic Roles and Inhibitors of DNMT1, DNMT3A, and DNMT3B in Acute Myeloid Leukaemia

Epigenetic alteration has been proposed to give rise to numerous classic hallmarks of cancer. Impaired DNA methylation plays a central role in the onset and progression of several types of malignancies, and DNA methylation is mediated by DNA methyltransferases (DNMTs) consisting of DNMT1, DNMT3A, an...

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Publicat a:Biomark Insights
Autors principals: Wong, Kah Keng, Lawrie, Charles H, Green, Tina M
Format: Artigo
Idioma:Inglês
Publicat: SAGE Publications 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6509988/
https://ncbi.nlm.nih.gov/pubmed/31105426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1177271919846454
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