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Friend or foe—Post-translational modifications as regulators of phase separation and RNP granule dynamics

Ribonucleoprotein (RNP) granules are membrane-less organelles consisting of RNA-binding proteins (RBPs) and RNA. RNA granules form through liquid–liquid phase separation (LLPS), whereby weak promiscuous interactions among RBPs and/or RNAs create a dense network of interacting macromolecules and driv...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Biol Chem
Prif Awduron: Hofweber, Mario, Dormann, Dorothee
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6509508/
https://ncbi.nlm.nih.gov/pubmed/30587571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.TM118.001189
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