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Friend or foe—Post-translational modifications as regulators of phase separation and RNP granule dynamics
Ribonucleoprotein (RNP) granules are membrane-less organelles consisting of RNA-binding proteins (RBPs) and RNA. RNA granules form through liquid–liquid phase separation (LLPS), whereby weak promiscuous interactions among RBPs and/or RNAs create a dense network of interacting macromolecules and driv...
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| Publicado no: | J Biol Chem |
|---|---|
| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6509508/ https://ncbi.nlm.nih.gov/pubmed/30587571 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.TM118.001189 |
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