Crystal structure of the TreS:Pep2 complex, initiating α-glucan synthesis in the GlgE pathway of mycobacteria

A growing body of evidence implicates the mycobacterial capsule, the outermost layer of the mycobacterial cell envelope, in modulation of the host immune response and virulence of mycobacteria. Mycobacteria synthesize the dominant capsule component, α(1→4)-linked glucan, via three interconnected and...

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Vydáno v:J Biol Chem
Hlavní autoři: Kermani, Ali A., Roy, Rana, Gopalasingam, Chai, Kocurek, Klaudia I., Patel, Trushar R., Alderwick, Luke J., Besra, Gurdyal S., Fütterer, Klaus
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2019
Témata:
Microbiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6509496/
https://ncbi.nlm.nih.gov/pubmed/30877199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.004297
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