Crystal structure of the TreS:Pep2 complex, initiating α-glucan synthesis in the GlgE pathway of mycobacteria

A growing body of evidence implicates the mycobacterial capsule, the outermost layer of the mycobacterial cell envelope, in modulation of the host immune response and virulence of mycobacteria. Mycobacteria synthesize the dominant capsule component, α(1→4)-linked glucan, via three interconnected and...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Kermani, Ali A., Roy, Rana, Gopalasingam, Chai, Kocurek, Klaudia I., Patel, Trushar R., Alderwick, Luke J., Besra, Gurdyal S., Fütterer, Klaus
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2019
Subjects:
Microbiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6509496/
https://ncbi.nlm.nih.gov/pubmed/30877199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.004297
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