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Synthesis of a Poly-hydroxypyrolidine-Based inhibitor of Mycobacterium tuberculosis GlgE

[Image: see text] Long treatment times, poor drug compliance, and natural selection during treatment of Mycobacterium tuberculosis (Mtb) have given rise to extensively drug-resistant tuberculosis (XDR-TB). As a result, there is a need to identify new antituberculosis drug targets. Mtb GlgE is a malt...

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Detalhes bibliográficos
Main Authors: Veleti, Sri Kumar, Lindenberger, Jared J., Thanna, Sandeep, Ronning, Donald R., Sucheck, Steven J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4201354/
https://ncbi.nlm.nih.gov/pubmed/25137149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo501481r
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