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Zwitterionic pyrrolidene-phosphonates: inhibitors of the glycoside hydrolase-like phosphorylase Streptomyces coelicolor GlgEI-V279S

We synthesized and evaluated new zwitterionic inhibitors against glycoside hydrolase-like phosphorylase Streptomyces coeticotor (Sco) GlgEI-V279S which plays a role in α-glucan biosynthesis. Sco GlgEI-V279S serves as a model enzyme for validated anti-tuberculosis (TB) target Mycobacterium tuberculos...

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Bibliografiske detaljer
Udgivet i:Org Biomol Chem
Main Authors: Veleti, Sri Kumar, Petit, Cecile, Ronning, Donald R., Sucheck, Steven J.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6169318/
https://ncbi.nlm.nih.gov/pubmed/28422240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7ob00388a
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