Phosphorylated tyrosine 93 of hepatitis C virus nonstructural protein 5A is essential for interaction with host c-Src and efficient viral replication

The hepatitis C virus (HCV) nonstructural protein 5A (NS5A) plays a key role in viral replication and virion assembly, and the regulation of the assembly process critically depends on phosphorylation of both serine and threonine residues in NS5A. We previously identified SRC proto-oncogene, nonrecep...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Klinker, Stefan, Stindt, Sabine, Gremer, Lothar, Bode, Johannes G., Gertzen, Christoph G. W., Gohlke, Holger, Weiergräber, Oliver H., Hoffmann, Silke, Willbold, Dieter
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Molecular Bases of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6509489/
https://ncbi.nlm.nih.gov/pubmed/30862675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.007656
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