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Arrestin recruitment and signaling by G protein-coupled receptor heteromers

G protein-coupled receptors (GPCR) have a long history of being considered a prime target for drug development to treat a plethora of diseases and disorders. In fact in 1827, the first approved therapeutic in the United States was morphine, a drug that targets a GPCR, namely the mu opioid receptor....

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Bibliografiske detaljer
Udgivet i:Neuropharmacology
Main Authors: Mores, Kendall L., Cassell, Robert J., van Rijn, Richard M.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6509026/
https://ncbi.nlm.nih.gov/pubmed/30419245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2018.11.010
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