Thyroid hormones induce doxorubicin chemosensitivity through enzymes involved in chemotherapy metabolism in lymphoma T cells

Thyroid hormones (THs) – 3,3′,5-triiodo-L-thyronine (T3) and L-thyroxine (T4) – are important regulators of the metabolism and physiology of most normal tissues. Cytochrome P450 family 3A members are drug metabolizing enzymes involved in the activation and detoxification of several drugs. CYP3A4 is...

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Udgivet i:Oncotarget
Main Authors: Díaz Flaqué, María Celeste, Cayrol, Maria Florencia, Sterle, Helena Andrea, del Rosario Aschero, María, Díaz Albuja, Johanna Abigail, Isse, Blanca, Farías, Ricardo Norberto, Cerchietti, Leandro, Rosemblit, Cinthia, Cremaschi, Graciela Alicia
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2019
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6508960/
https://ncbi.nlm.nih.gov/pubmed/31105885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26890
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