Integrin αvβ3 acting as membrane receptor for thyroid hormones mediates angiogenesis in malignant T cells

The interaction of lymphoid tumor cells with components of the extracellular matrix via integrin αvβ3 allows tumor survival and growth. This integrin was demonstrated to be the membrane receptor for thyroid hormones (THs) in several tissues. We found that THs, acting as soluble integrin αvβ3 ligands...

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Veröffentlicht in:Blood
Hauptverfasser: Cayrol, Florencia, Díaz Flaqué, María Celeste, Fernando, Tharu, Yang, Shao Ning, Sterle, Helena Andrea, Bolontrade, Marcela, Amorós, Mariana, Isse, Blanca, Farías, Ricardo Norberto, Ahn, Haelee, Tian, Ye F., Tabbò, Fabrizio, Singh, Ankur, Inghirami, Giorgio, Cerchietti, Leandro, Cremaschi, Graciela Alicia
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2015
Schlagworte:
Lymphoid Neoplasia
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4311229/
https://ncbi.nlm.nih.gov/pubmed/25488971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-07-587337
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