Integrin αvβ3 acting as membrane receptor for thyroid hormones mediates angiogenesis in malignant T cells

The interaction of lymphoid tumor cells with components of the extracellular matrix via integrin αvβ3 allows tumor survival and growth. This integrin was demonstrated to be the membrane receptor for thyroid hormones (THs) in several tissues. We found that THs, acting as soluble integrin αvβ3 ligands...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Cayrol, Florencia, Díaz Flaqué, María Celeste, Fernando, Tharu, Yang, Shao Ning, Sterle, Helena Andrea, Bolontrade, Marcela, Amorós, Mariana, Isse, Blanca, Farías, Ricardo Norberto, Ahn, Haelee, Tian, Ye F., Tabbò, Fabrizio, Singh, Ankur, Inghirami, Giorgio, Cerchietti, Leandro, Cremaschi, Graciela Alicia
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2015
Assuntos:
Lymphoid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4311229/
https://ncbi.nlm.nih.gov/pubmed/25488971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-07-587337
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