Progesterone Receptor Induces ErbB-2 Nuclear Translocation To Promote Breast Cancer Growth via a Novel Transcriptional Effect: ErbB-2 Function as a Coactivator of Stat3

Progesterone receptor (PR) and ErbB-2 bidirectional cross talk participates in breast cancer development. Here, we identified a new mechanism of the PR and ErbB-2 interaction involving the PR induction of ErbB-2 nuclear translocation and the assembly of a transcriptional complex in which ErbB-2 acts...

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Auteurs principaux: Béguelin, Wendy, Díaz Flaqué, María Celeste, Proietti, Cecilia J., Cayrol, Florencia, Rivas, Martín A., Tkach, Mercedes, Rosemblit, Cinthia, Tocci, Johanna M., Charreau, Eduardo H., Schillaci, Roxana, Elizalde, Patricia V.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2010
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Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2976427/
https://ncbi.nlm.nih.gov/pubmed/20876300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00012-10
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