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Influence of multiple-sequence-alignment depth on Potts statistical models of protein covariation
Potts statistical models have become a popular and promising way to analyze mutational covariation in protein multiple sequence alignments (MSAs) in order to understand protein structure, function and fitness. But the statistical limitations of these models, which can have millions of parameters and...
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| Publicado no: | Phys Rev E |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6508952/ https://ncbi.nlm.nih.gov/pubmed/30999494 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1103/PhysRevE.99.032405 |
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