A27 ERK/MAPK SIGNALING PROMOTES GOBLET CELL DIFFERENTIATION BY INHIBITING THE NOTCH PATHWAY

BACKGROUND: Several mouse genetic models have suggested an important role for EGF, Wnt, BMP/TGFbeta and Notch signaling pathways in the renewal and differentiation of intestinal stem cells. EGF and its orthologs TGFalpha and epiregulin are factors regulating growth in epithelial tissues through acti...

詳細記述

保存先:
書誌詳細
出版年:J Can Assoc Gastroenterol
主要な著者: Gagné Sansfaçon, J, Langlois, A, Langlois, M, Beaudry, K, Rivard, N
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2018
主題:
Paper Sessions
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6508159/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jcag/gwy009.027
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