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Inhibition of MAPK/ERK pathway promotes oligodendrocytes generation and recovery of demyelinating diseases

Oligodendrocytes (OLs) are the myelinating glia of the central nervous system. Injury to OLs causes myelin loss. In demyelinating diseases, such as multiple sclerosis, the remyelination is hindered principally due to a failure of the oligodendrocyte precursor cells (OPCs) to differentiate into matur...

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Bibliografiske detaljer
Udgivet i:Glia
Main Authors: Suo, Na, Guo, Yu‐e, He, Bingqing, Gu, Haifeng, Xie, Xin
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley & Sons, Inc. 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6593996/
https://ncbi.nlm.nih.gov/pubmed/30815939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.23606
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