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Inhibition of MAPK/ERK pathway promotes oligodendrocytes generation and recovery of demyelinating diseases

Oligodendrocytes (OLs) are the myelinating glia of the central nervous system. Injury to OLs causes myelin loss. In demyelinating diseases, such as multiple sclerosis, the remyelination is hindered principally due to a failure of the oligodendrocyte precursor cells (OPCs) to differentiate into matur...

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Publicat a:Glia
Autors principals: Suo, Na, Guo, Yu‐e, He, Bingqing, Gu, Haifeng, Xie, Xin
Format: Artigo
Idioma:Inglês
Publicat: John Wiley & Sons, Inc. 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6593996/
https://ncbi.nlm.nih.gov/pubmed/30815939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.23606
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