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Inhibition of MAPK/ERK pathway promotes oligodendrocytes generation and recovery of demyelinating diseases
Oligodendrocytes (OLs) are the myelinating glia of the central nervous system. Injury to OLs causes myelin loss. In demyelinating diseases, such as multiple sclerosis, the remyelination is hindered principally due to a failure of the oligodendrocyte precursor cells (OPCs) to differentiate into matur...
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| Publicado no: | Glia |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley & Sons, Inc.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6593996/ https://ncbi.nlm.nih.gov/pubmed/30815939 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.23606 |
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