A27 ERK/MAPK SIGNALING PROMOTES GOBLET CELL DIFFERENTIATION BY INHIBITING THE NOTCH PATHWAY

BACKGROUND: Several mouse genetic models have suggested an important role for EGF, Wnt, BMP/TGFbeta and Notch signaling pathways in the renewal and differentiation of intestinal stem cells. EGF and its orthologs TGFalpha and epiregulin are factors regulating growth in epithelial tissues through acti...

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Detalhes bibliográficos
Publicado no:J Can Assoc Gastroenterol
Main Authors: Gagné Sansfaçon, J, Langlois, A, Langlois, M, Beaudry, K, Rivard, N
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Paper Sessions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6508159/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jcag/gwy009.027
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