Ethanol Negatively Regulates Hepatic Differentiation of hESC by Inhibition of the MAPK/ERK Signaling Pathway In Vitro

BACKGROUND: Alcohol insult triggers complex events in the liver, promoting fibrogenic/inflammatory signals and in more advanced cases, aberrant matrix deposition. It is well accepted that the regenerative capacity of the adult liver is impaired during alcohol injury. The liver progenitor/stem cells...

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Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Gao, Wei, Zhou, Ping, Ma, Xiaocui, Tschudy-Seney, Benjamin, Chen, Jiamei, Magner, Nataly L., Revzin, Alexander, Nolta, Jan A., Zern, Mark A., Duan, Yuyou
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4231066/
https://ncbi.nlm.nih.gov/pubmed/25393427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0112698
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