Salvianolic Acid B Enhances Hepatic Differentiation of Human Embryonic Stem Cells Through Upregulation of WNT Pathway and Inhibition of Notch Pathway

Hepatocytes differentiated from human embryonic stem cells (ESCs) could provide a powerful tool for enabling cell-based therapies, studying the mechanisms underlying human liver development and disease, and testing the efficacy and safety of pharmaceuticals. However, currently most in vitro protocol...

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Bibliographische Detailangaben
Veröffentlicht in:Stem Cells Dev
Hauptverfasser: Chen, Jiamei, Tschudy-Seney, Benjamin, Ma, Xiaocui, Zern, Mark A., Liu, Ping, Duan, Yuyou
Format: Artigo
Sprache:Inglês
Veröffentlicht: Mary Ann Liebert, Inc. 2018
Schlagworte:
Original Research Reports
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5813732/
https://ncbi.nlm.nih.gov/pubmed/29256825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2017.0168
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