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A169 FLUORESCENT LABELING OF THE HCV HELICASE TO MONITOR NUCLEIC ACID UNWINDING BY FRET
BACKGROUND: The hepatitis C virus (HCV) non-structural protein 3 (NS3) contains a helicase activity essential for viral replication. The helicase binds to single-stranded (ss) regions of nucleic acids and unwinds duplexes in an ATP-dependent manner. The mechanism by which the helicase disrupts RNA s...
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| 出版年: | J Can Assoc Gastroenterol |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6508019/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jcag/gwy008.170 |
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