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A208 SHP-2 PHOSPHATASE PREVENTS SENESCENCE IN NORMAL AND TUMOR INTESTINAL EPITHELIAL CELLS
BACKGROUND: The protein tyrosine phosphatase SHP-2 is known to regulate many cellular functions including growth, differentiation and survival. Interestingly, a gain-of-function mutation (residue E76K) in the gene encoding SHP-2 has been found in some colorectal cancers. Importantly, intestinal epit...
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| Publicado no: | J Can Assoc Gastroenterol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6507755/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jcag/gwy008.209 |
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