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Surface patches on recombinant erythropoietin predict protein solubility: engineering proteins to minimise aggregation
BACKGROUND: Protein solubility characteristics are important determinants of success for recombinant proteins in relation to expression, purification, storage and administration. Escherichia coli offers a cost-efficient expression system. An important limitation, whether for biophysical studies or i...
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| Pubblicato in: | BMC Biotechnol |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6507049/ https://ncbi.nlm.nih.gov/pubmed/31072369 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12896-019-0520-z |
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