Engineering of recombinant soluble CD46: an inhibitor of complement activation.

Human CD46 (membrane cofactor protein) is a type 1 glycoprotein that functions to protect autologous cells from complement-mediated damage by binding C3b and C4b for their factor I-mediated cleavage. We now describe the production and function of recombinant soluble CD46 (rsCD46), which was produced...

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Detalhes bibliográficos
Main Authors: Christiansen, D, Milland, J, Thorley, B R, McKenzie, I F, Mottram, P L, Purcell, L J, Loveland, B E
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1384101/
https://ncbi.nlm.nih.gov/pubmed/8778018
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