Blocking measles virus infection with a recombinant soluble form of, or monoclonal antibodies against, membrane cofactor protein of complement (CD46).

Human membrane cofactor protein (MCP, CD46) functions as an inhibitor of the complement (C) cascade to protect host cells from C attack, and as a receptor for measles virus (MV). Normal human sera contains 10-60 ng/ml of naturally produced soluble forms of MCP, which is also a cofactor for the facto...

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Detalhes bibliográficos
Main Authors: Seya, T, Kurita, M, Hara, T, Iwata, K, Semba, T, Hatanaka, M, Matsumoto, M, Yanagi, Y, Ueda, S, Nagasawa, S
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1415153/
https://ncbi.nlm.nih.gov/pubmed/7790036
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