Molecular remodelling of human CD46 for xenotransplantation: designing a potent complement regulator without measles virus receptor activity

In pig-to-human discordant xenotransplantation, human complement (C) is a major barrier to long survival of xenografts. The current idea on how to cope with this barrier is that human complement regulatory proteins are forcibly expressed on xenografts to serve as safeguards against host C-induced hy...

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Detalhes bibliográficos
Main Authors: Begum, N A, Murakami, Y, Mikata, S, Matsumoto, M, Hatanaka, M, Nagasawa, S, Kinoshita, T, Seya, T
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2000
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2326985/
https://ncbi.nlm.nih.gov/pubmed/10809968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.2000.00999.x
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