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DNA Polymerase alpha is essential for intracellular amplification of hepatitis B virus covalently closed circular DNA
Persistent hepatitis B virus (HBV) infection relies on the establishment and maintenance of covalently closed circular (ccc) DNA, a 3.2 kb episome that serves as a viral transcription template, in the nucleus of an infected hepatocyte. Although evidence suggests that cccDNA is the repair product of...
Guardat en:
| Publicat a: | PLoS Pathog |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6505960/ https://ncbi.nlm.nih.gov/pubmed/31026293 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007742 |
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