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Brain activity associated with pain in inherited erythromelalgia: stimulus-free pain engages brain areas involved in valuation and learning

Inherited erythromelalgia (IEM) is a chronic pain disorder caused by gain-of-function mutations of peripheral sodium channel Nav1.7, in which warmth triggers severe pain. Little is known about the brain representation of pain in IEM. Here we study two subjects with the IEM Nav1.7-S241T mutation usin...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Neurobiol Pain
Egile Nagusiak: Geha, Paul, Schulman, Betsy R., Dib-Hajj, Sulayman D., Waxman, Stephen G.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Elsevier 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6505710/
https://ncbi.nlm.nih.gov/pubmed/31080911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ynpai.2018.01.002
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