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Mutation I136V alters electrophysiological properties of the Na(V)1.7 channel in a family with onset of erythromelalgia in the second decade

BACKGROUND: Primary erythromelalgia is an autosomal dominant pain disorder characterized by burning pain and skin redness in the extremities, with onset of symptoms during the first decade in the families whose mutations have been physiologically studied to date. Several mutations of voltage-gated N...

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Detalhes bibliográficos
Main Authors: Cheng, Xiaoyang, Dib-Hajj, Sulayman D, Tyrrell, Lynda, Waxman, Stephen G
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2262064/
https://ncbi.nlm.nih.gov/pubmed/18171466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-4-1
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