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Computational analysis of data from a genome-wide screening identifies new PARP1 functional interactors as potential therapeutic targets

Knowledge of interaction network between different proteins can be a useful tool in cancer therapy. To develop new therapeutic treatments, understanding how these proteins contribute to dysregulated cellular pathways is an important task. PARP1 inhibitors are drugs used in cancer therapy, in particu...

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Publicat a:Oncotarget
Autors principals: Lodovichi, Samuele, Mercatanti, Alberto, Cervelli, Tiziana, Galli, Alvaro
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6505629/
https://ncbi.nlm.nih.gov/pubmed/31105872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26812
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