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Computational analysis of data from a genome-wide screening identifies new PARP1 functional interactors as potential therapeutic targets

Knowledge of interaction network between different proteins can be a useful tool in cancer therapy. To develop new therapeutic treatments, understanding how these proteins contribute to dysregulated cellular pathways is an important task. PARP1 inhibitors are drugs used in cancer therapy, in particu...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Lodovichi, Samuele, Mercatanti, Alberto, Cervelli, Tiziana, Galli, Alvaro
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6505629/
https://ncbi.nlm.nih.gov/pubmed/31105872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26812
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