Llwytho...
Inverted terminal repeats of adeno-associated virus decrease random integration of a gene targeting fragment in Saccharomyces cerevisiae
BACKGROUND: Homologous recombination mediated gene targeting is still too inefficient to be applied extensively in genomics and gene therapy. Although sequence-specific nucleases could greatly stimulate gene targeting efficiency, the off-target cleavage sites of these nucleases highlighted the risk...
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Fformat: | Artigo |
Iaith: | Inglês |
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BioMed Central
2014
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Pynciau: | |
Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3925961/ https://ncbi.nlm.nih.gov/pubmed/24521444 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2199-15-5 |
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