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Formation of AAV Single Stranded DNA Genome from a Circular Plasmid in Saccharomyces cerevisiae

Adeno-associated virus (AAV)-based vectors are promising tools for targeted transfer in gene therapy studies. Many efforts have been accomplished to improve production and purification methods. We thought to develop a simple eukaryotic system allowing AAV replication which could provide an excellent...

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Detalhes bibliográficos
Main Authors: Cervelli, Tiziana, Backovic, Ana, Galli, Alvaro
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3154452/
https://ncbi.nlm.nih.gov/pubmed/21853137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023474
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