Cortical Excitability and Activation of TrkB Signaling During Rebound Slow Oscillations Are Critical for Rapid Antidepressant Responses

Rapid antidepressant effects of ketamine become most evident when its psychotomimetic effects subside, but the neurobiological basis of this “lag” remains unclear. Laughing gas (N(2)O), another NMDA-R (N-methyl-d-aspartate receptor) blocker, has been reported to bring antidepressant effects rapidly...

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Bibliografische gegevens
Gepubliceerd in:Mol Neurobiol
Hoofdauteurs: Kohtala, Samuel, Theilmann, Wiebke, Rosenholm, Marko, Penna, Leena, Karabulut, Gulsum, Uusitalo, Salla, Järventausta, Kaija, Yli-Hankala, Arvi, Yalcin, Ipek, Matsui, Nobuaki, Wigren, Henna-Kaisa, Rantamäki, Tomi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Springer US 2018
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6505519/
https://ncbi.nlm.nih.gov/pubmed/30288695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-018-1364-6
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