Cortical Excitability and Activation of TrkB Signaling During Rebound Slow Oscillations Are Critical for Rapid Antidepressant Responses

Rapid antidepressant effects of ketamine become most evident when its psychotomimetic effects subside, but the neurobiological basis of this “lag” remains unclear. Laughing gas (N(2)O), another NMDA-R (N-methyl-d-aspartate receptor) blocker, has been reported to bring antidepressant effects rapidly...

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Detalhes bibliográficos
Publicado no:Mol Neurobiol
Main Authors: Kohtala, Samuel, Theilmann, Wiebke, Rosenholm, Marko, Penna, Leena, Karabulut, Gulsum, Uusitalo, Salla, Järventausta, Kaija, Yli-Hankala, Arvi, Yalcin, Ipek, Matsui, Nobuaki, Wigren, Henna-Kaisa, Rantamäki, Tomi
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6505519/
https://ncbi.nlm.nih.gov/pubmed/30288695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-018-1364-6
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